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Symbol Name ID |
Kcnj8
potassium inwardly-rectifying channel, subfamily J, member 8 MGI:1100508 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Mouse Phenotypes | cardiovascular system phenotype |
abnormal aorta morphology |
aortic arch dilation |
increased myocardial fiber size |
increased heart weight |
enlarged heart |
cardiac hypertrophy |
aortic valve stenosis |
abnormal heart left ventricle morphology |
dilated heart left ventricle |
increased cardiac output |
abnormal heart echocardiography feature |
aortic valve regurgitation |
irregular heartbeat |
abnormal myocardial fiber physiology |
hypotension |
hypertension |
abnormal vascular smooth muscle physiology |
decreased vasoconstriction |
increased vasodilation |
coronary artery spasm |
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| Availability | Mouse Genotype | |||||||||||||||||||||
| Kcnj8tm1Sse/Kcnj8tm1Sse | * | |||||||||||||||||||||
| Kcnj8em1Nich/Kcnj8+ | ||||||||||||||||||||||
| Tg(ACTB-EGFP,-Kcnj8)1Nich/0 Tg(Myh11-icre/ERT2)1Soff/0 (conditional) |
* | |||||||||||||||||||||
| Tg(ACTB-EGFP,-Kcnj8*G343D)9Nich/0 Tg(Myh11-icre/ERT2)1Soff/0 (conditional) |
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| Tg(ACTB-EGFP,-Kcnj8*Q53R*G343D)1Nich/0 Tg(Myh11-icre/ERT2)1Soff/0 (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/30/2024 MGI 6.23 |
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